Enalapril (MK-421) maleate is an angiotensin-converting enzyme (ACE) inhibitor and the active metabolite of enalapril. This prodrug is rapidly metabolized in the liver to enalaprilat after oral administration. It is a potent, competitive inhibitor of ACE, an enzyme crucial for converting angiotensin I to angiotensin II, which regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS).
- Treats essential or renovascular hypertension
- Treats symptomatic congestive heart failure
- Functions as a potent, competitive ACE inhibitor
- Metabolized to enalaprilat in the liver
- For research use only